SCHREINER LAB
Our aim is to uncover the neural dynamics mediating memory consolidation, hence the strengthening of memories during sleep. In particular we focus on how sleep-related neural activity facilitates memory reactivation and the behavioral expressions of memory consolidation in humans. How are reactivation processes and their coordination across the sleeping brain achieved? What roles do cortical slow oscillations, thalamocortical spindles, and hippocampal ripples play in this context? We are furthermore interested in brain-body interactions supporting the memory function of sleep. In particular, our aim is to decipher the role of respiration in governing the interplay of sleep related oscillations and memory reactivation. To what extend is respiration influencing the emergence of slow oscillations, spindles and ripples? How does respiration exert its influence on sleep related oscillations? Can respiration during sleep be harnessed to counteract memory decline associated with aging? Our research combines behavioral testing, electrophysiological recordings (intracranial and scalp EEG, MEG), and peripheral physiological recordings (e.g., respiration) to address these questions.